How Do Hair Follicles Die?

Photo of author

By admin

As we age, many of us may experience the frustrating and sometimes distressing process of hair follicles dying. Hair follicles are vital to the growth and maintenance of healthy, strong hair, so when they begin to die, it can result in thinning and balding. There are a variety of reasons why hair follicles die, including genetic factors, hormonal changes, and environmental stressors. Understanding the mechanisms behind hair follicle death can help individuals take proactive steps in preventing or slowing down this natural process. In this article, we will explore how hair follicles die and what can be done to potentially preserve their health and vitality.


The Lifecycle of Hair Follicles: Understanding the Growth and Decline Process

Understanding the lifecycle of hair follicles is essential in maintaining healthy hair and addressing issues such as hair loss and thinning. The growth and decline process of hair follicles is a complex yet fascinating phenomenon that involves various stages.

The Lifecycle of Hair Follicles

The lifecycle of hair follicles comprises three main phases:

  1. Anagen Phase: This is the active growth phase of hair follicles, during which hair grows approximately 1 cm every 28 days. The duration of the anagen phase varies from person to person, and it can last anywhere from 2 to 7 years. Hair follicles in this phase are constantly dividing and producing new hair cells, leading to visible hair growth.
  2. Catagen Phase: The catagen phase is a transitional phase during which hair follicles shrink and detach from the dermal papilla. This phase marks the end of active hair growth, and it typically lasts for about 2-3 weeks. During the catagen phase, the hair follicle is no longer producing hair, and it prepares for the next phase.
  3. Telogen Phase: In the telogen phase, also known as the resting phase, the hair follicle remains dormant for about 3 months. At this stage, the old hair is shed, and new hair begins to grow as the cycle starts anew. It’s normal to shed around 50-100 hairs a day during the telogen phase as part of the natural shedding and regrowth process.

Understanding the lifecycle of hair follicles can provide insights into the causes of hair loss and the effectiveness of various hair care treatments. By recognizing the stages of hair growth and decline, individuals can take proactive steps to promote healthy hair and address any issues related to hair loss.

Genetic Factors Contributing to Hair Follicle Degeneration

Hair follicle degeneration is a complex process influenced by various genetic factors. Understanding these genetic factors is crucial in developing effective treatments for conditions such as male pattern baldness and alopecia.

One of the key genetic factors contributing to hair follicle degeneration is the presence of androgen receptors. Androgen receptors are proteins that bind to hormones such as testosterone, and their activity has been linked to hair loss. Research has shown that individuals with a genetic predisposition for high levels of androgen receptors in their hair follicles are more likely to experience hair loss.

In addition to androgen receptors, variations in the AR gene have also been linked to hair follicle degeneration. The AR gene provides instructions for making the androgen receptor, and certain mutations in this gene can lead to an increased sensitivity to androgens, ultimately contributing to hair loss.

Similar Articles -   DOs and DON’Ts after a Hair Transplant

Table: Genetic Factors Influencing Hair Follicle Degeneration

Genetic FactorImpact on Hair Follicle Degeneration
Androgen ReceptorsHigh levels linked to increased hair loss
AR Gene VariationsMutations can lead to increased sensitivity to androgens

Furthermore, a study published in the Journal of Investigative Dermatology identified a specific gene, known as the trichohyalin gene, that plays a role in hair follicle degeneration. Variations in this gene have been associated with certain forms of alopecia, shedding light on the genetic basis of this condition.

In conclusion, genetic factors significantly contribute to hair follicle degeneration, and understanding the role of androgen receptors, AR gene variations, and other specific genes such as trichohyalin is essential in developing targeted therapies for hair loss conditions.

The Role of Hormonal Imbalance in Hair Follicle Deterioration

Hormonal imbalance can have a significant impact on the health of hair follicles. When the body’s hormonal levels are not properly balanced, it can lead to a range of hair-related issues, from thinning and breakage to overall deterioration of the hair follicles.

One of the key hormones that plays a role in hair follicle health is dihydrotestosterone (DHT). When levels of DHT are too high, it can bind to the receptors in the hair follicles and cause them to shrink. This can ultimately lead to hair thinning and eventual hair loss.

In addition to DHT, other hormones such as estrogen and progesterone also play a role in maintaining healthy hair follicles. When these hormones are out of balance, it can lead to conditions such as female pattern hair loss or telogen effluvium.

It’s important to address hormonal imbalances in order to maintain the health of the hair follicles. This can be done through a combination of lifestyle changes, dietary adjustments, and, in some cases, medical intervention.


In conclusion, hormonal imbalance can have a significant impact on the health of hair follicles. It’s important to address these imbalances in order to maintain healthy, strong hair. By understanding the role of hormones in hair follicle deterioration, individuals can take proactive steps to maintain their overall hair health.

Environmental and Lifestyle Influences on Hair Follicle Health

The health of our hair follicles is influenced by a variety of environmental and lifestyle factors. Understanding these influences can help us make informed choices to support the health of our hair.

Environmental Influences

1. **Pollution**: Air pollution can have a negative impact on hair follicle health. Fine particulate matter in the air can clog pores and lead to scalp irritation.

2. **UV Exposure**: Excessive sun exposure can damage the hair follicles, leading to dryness and breakage.

3. **Climate**: Extreme weather conditions, such as excessive heat or cold, can stress the hair follicles and contribute to hair loss.

Lifestyle Influences

1. **Diet**: A diet lacking in essential nutrients, such as **protein**, **iron**, and **vitamins**, can adversely affect hair follicle health.

2. **Stress**: Chronic stress can disrupt the hair growth cycle and lead to increased shedding.

3. **Hair Care Practices**: Overuse of heat styling tools, harsh chemical treatments, and tight hairstyles can damage the hair follicles.

Supporting Hair Follicle Health

1. **Balanced Diet**: Consuming a variety of nutrient-dense foods can provide the essential building blocks for healthy hair follicles.

2. **Stress Management**: Practicing relaxation techniques and engaging in regular physical activity can help manage stress and support hair health.

3. **Gentle Hair Care**: Using gentle, sulfate-free shampoos and minimizing heat and chemical damage can protect the hair follicles.

Environmental InfluencesLifestyle Influences
UV ExposureStress
ClimateHair Care Practices

By addressing environmental and lifestyle influences on hair follicle health, we can support the strength and vitality of our hair.

The Impact of Aging on Hair Follicle Viability

As we age, our bodies undergo various changes, and one of the most noticeable changes can be seen in the health and vitality of our hair follicles. The impact of aging on hair follicle viability is a topic of great interest, as many individuals experience changes in the thickness, texture, and overall health of their hair as they grow older.

One of the key factors that contribute to the decline in hair follicle viability is the decrease in the production of essential proteins and nutrients that are necessary for maintaining healthy hair growth. As we age, the body’s ability to produce these vital resources diminishes, leading to weaker, more brittle hair follicles that are more prone to breakage and thinning.

Similar Articles -   Hairline Implants Change How You Look and How You Feel

Furthermore, the reduction in blood circulation to the scalp, which naturally occurs as we age, can also have a negative impact on hair follicle viability. Diminished blood flow means that the hair follicles are not receiving an adequate supply of oxygen and nutrients, which can result in a decrease in their overall health and vitality.

It is also important to consider the role of hormonal changes in the aging process and their impact on hair follicle viability. Fluctuations in hormone levels, particularly the decrease in estrogen and progesterone in women and the increase in dihydrotestosterone (DHT) in men, can contribute to hair thinning and loss as we age.


In conclusion, the impact of aging on hair follicle viability is a complex process that involves a combination of physiological, hormonal, and environmental factors. Understanding these changes and their effects on hair health is crucial for developing effective strategies to maintain and improve hair follicle viability as we age.

Autoimmune Disorders and Their Effect on Hair Follicle Survival

Autoimmune disorders are a group of conditions in which the immune system mistakenly attacks the body’s own cells. This can have a significant impact on the body’s ability to function properly, and can also result in a number of symptoms, including hair loss. In this article, we will explore the connection between autoimmune disorders and their effect on hair follicle survival.

The Immune System and Hair Follicles

The immune system is responsible for protecting the body from harmful substances, such as bacteria and viruses. However, in the case of autoimmune disorders, the immune system becomes overactive and begins to attack healthy cells. In the context of hair follicles, this can lead to inflammation and damage, which in turn can disrupt the normal hair growth cycle.

Common Autoimmune Disorders and Hair Loss

There are several autoimmune disorders that have been linked to hair loss, including alopecia areata, lupus, and thyroid disorders. In the case of alopecia areata, the immune system targets the hair follicles, causing hair to fall out in small, round patches. Lupus, on the other hand, can lead to widespread hair loss as a result of inflammation and scarring. Thyroid disorders, such as Hashimoto’s disease and Graves’ disease, can also cause hair loss due to the impact they have on hormone levels and the immune system.

“The immune system plays a complex role in the regulation of hair follicle survival, and disturbances in its normal functioning can have profound effects on hair health.”

Treatment and Management

Managing hair loss associated with autoimmune disorders can be challenging, as it often involves addressing the underlying autoimmune condition. This may include the use of immunosuppressant medications to reduce the activity of the immune system, as well as other treatments aimed at controlling inflammation and promoting hair growth. Additionally, support and counseling may be beneficial for individuals experiencing hair loss as a result of autoimmune disorders.

Autoimmune DisorderEffect on Hair Follicles
Alopecia AreataTargets hair follicles, leading to patchy hair loss
LupusCauses widespread hair loss due to inflammation and scarring
Thyroid DisordersImpact hormone levels and immune system, resulting in hair loss

In conclusion, autoimmune disorders can have a profound effect on hair follicle survival, leading to a range of symptoms including hair loss. Understanding the connection between autoimmune disorders and hair health is crucial for effective management and treatment.

Hair Care Practices and Their Potential Contribution to Follicle Damage

Healthy and well-maintained hair is often seen as a symbol of beauty and vitality. However, many common hair care practices may actually contribute to follicle damage, leading to issues such as hair breakage, thinning, and loss. It is important to understand the potential impact of different hair care practices on the health of our hair follicles in order to make informed choices about our hair care routine.

Factors Contributing to Follicle Damage:

  1. Heat styling: Excessive use of hair dryers, straightening irons, and curling wands can lead to damage to the hair follicles, causing them to become weak and prone to breakage. It is important to use these tools on a low or medium heat setting and to use a heat protectant spray to minimize damage.
  2. Chemical treatments: Hair coloring, bleaching, and perming can all cause damage to the hair follicles, leading to dryness, breakage, and in severe cases, hair loss. It is important to follow the instructions provided by professionals and to give the hair time to recover between treatments.
  3. Tight hairstyles: Wearing hairstyles that pull on the hair, such as tight ponytails, braids, or cornrows, can lead to a condition known as traction alopecia, where the hair follicles become damaged and the hair begins to thin and fall out. Opt for looser hairstyles and give your hair frequent breaks from tight styles to minimize this risk.
Similar Articles -   Can I take whey protein after a hair transplant?

By understanding the potential impact of these and other hair care practices on the health of our hair follicles, we can make informed choices about how to care for our hair in a way that promotes strong, healthy hair growth.

Nutritional Deficiencies and Hair Follicle Degeneration

Proper nutrition plays a crucial role in maintaining the health of our hair follicles. Nutritional deficiencies can lead to hair follicle degeneration, which in turn can result in hair loss and other scalp issues. In this article, we will explore the impact of various nutritional deficiencies on hair follicle health.

Vitamin Deficiencies

Vitamins are essential for maintaining healthy hair follicles. A deficiency in vitamin A can lead to dry, rough hair and a flaky scalp. Vitamin C is important for collagen production, which is vital for hair structure and growth. Lack of vitamin C can lead to weak, brittle hair. Vitamin D is also crucial for hair follicle stimulation and can result in hair loss if deficient.

Mineral Deficiencies

Minerals such as iron and zinc are important for hair follicle health. Iron deficiency can lead to anemia and hair loss, while zinc deficiency can result in poor hair growth and scalp conditions. Selenium is another essential mineral that contributes to the health of hair follicles.

Protein Deficiency

Protein is the building block of hair, and a deficiency in protein can lead to weak, brittle hair and hair loss. It is important to consume adequate amounts of protein for maintaining healthy hair follicles.

NutrientImpact on Hair Follicles
Vitamin ADry, rough hair and flaky scalp
Vitamin CWeak, brittle hair
Vitamin DHair loss
IronAnemia and hair loss
ZincPoor hair growth and scalp conditions
ProteinWeak, brittle hair and hair loss

Medical Treatments and Therapies for Restoring Dying Hair Follicles

For individuals experiencing hair loss, the search for effective medical treatments and therapies to restore dying hair follicles is of utmost importance. While there are many products and procedures on the market claiming to promote hair growth, it is essential to understand the science behind these treatments and consult with a qualified medical professional before starting any regimen.

Understanding the Science of Hair Loss

Genetics play a significant role in hair loss, as certain genes can make individuals more susceptible to pattern baldness. Additionally, hormonal imbalances, medical conditions, and certain medications can contribute to the weakening and dying of hair follicles over time.

When it comes to medical treatments for restoring dying hair follicles, there are several options available, depending on the severity and underlying cause of the hair loss. Topical treatments such as minoxidil can help stimulate hair growth by increasing blood flow to the scalp and providing essential nutrients to the follicles. Oral medications like finasteride can also be prescribed to prevent further hair loss and promote regrowth.

Therapies and Procedures

In more severe cases of hair loss, hair transplant surgery may be recommended to restore dying follicles. This involves moving healthy hair follicles from one area of the scalp to the balding or thinning areas, creating a natural-looking hairline and denser hair growth. Additionally, platelet-rich plasma (PRP) therapy has gained popularity as a non-invasive treatment option for stimulating hair growth by using the patient’s own blood plasma to promote cell regeneration.

Overall, restoring dying hair follicles through medical treatments and therapies requires a comprehensive approach tailored to the individual’s specific needs and goals. Consulting with a dermatologist or hair restoration specialist is the first step in creating a personalized treatment plan that addresses the underlying cause of hair loss and promotes long-term, sustainable results.

Frequently Asked Questions

Do hair follicles die naturally?

Yes, hair follicles can naturally stop producing hair, leading to hair loss and eventually the death of the follicle.

Can hair follicles be revived once they die?

Unfortunately, once a hair follicle is dead, it cannot be revived. However, there are treatments and procedures that can stimulate new follicle growth in surrounding areas.

What causes hair follicles to die?

Hair follicles can die due to aging, hormonal changes, genetics, and certain medical conditions. Additionally, excessive tension on the hair shaft, such as tight hairstyles, can contribute to follicle damage and potential death.

Can poor nutrition lead to the death of hair follicles?

Yes, inadequate nutrition, specifically deficiencies in essential vitamins and minerals, can impact the health of hair follicles and potentially lead to their death.

Is there a way to prevent hair follicles from dying?

While some factors contributing to hair follicle death, such as genetics, cannot be controlled, maintaining a healthy lifestyle, avoiding excessive heat and chemical damage, and using gentle hair care practices can help preserve the health of follicles.

Do hair follicles die permanently after hair loss?

Hair follicles can experience a temporary dormancy phase and potentially reinitiate hair growth. However, if follicles remain dormant for an extended period, they may become permanently inactive or die.

Can stress cause the death of hair follicles?

Extended periods of high stress can impact the hair growth cycle and contribute to hair loss, potentially leading to the death of follicles. Stress reduction techniques and self-care practices may aid in mitigating this effect.

Do hair treatments and products contribute to follicle death?

Certain harsh chemical treatments and products, when used in excess or without proper care, can damage hair and follicles, eventually leading to follicle death. It’s important to use these treatments and products judiciously and follow recommended guidelines.

Can medical conditions lead to the death of hair follicles?

Certain medical conditions, such as alopecia areata and autoimmune disorders, can cause the immune system to mistakenly attack hair follicles, leading to their death. Consulting with a healthcare professional is important for managing such conditions.

Do environmental factors play a role in hair follicle death?

Environmental factors, such as pollution, UV radiation, and exposure to harsh weather conditions, can have a detrimental impact on the health of hair follicles, potentially contributing to their death. Protective measures, like wearing hats and using hair care products with UV protection, can help mitigate these effects.

Leave a Comment